Indian Journal of Science & Research

Title: COMPARATIVE ANALYSIS OF .NET CORE VS. .NET FRAMEWORK FOR DEVELOPING C# APPLICATIONS: DIFFERENCES AND ADVANTAGES
Author: Poe Ei Phyu, Thet Thet Aung, Khaing Thazin Nwe, Sharo Paw, Hlaing Htake Khaung Tin*
Keyword: .NET, C#, .NET Core, .NET Framework, Case Studies, Differences.
Page No: 01-09

Abstract: In the changing landscape of the.NET ecosystem software developers often face the decision of choosing between.NET Core and.NET Framework for developing C# applications. This study delves into the nua nces and benefits of opting for .NET Core over the Framework. It kicks things o? with a comparison that scrutinizes the architectural disparities, performance benchmarks, platform support, and dependency management features across both frameworks. The analysis focuses closely the support from the ecosystem and community to measure the presence of libraries and frameworks well as community involvement for both.NET. .Net Frameworks. It also delves into considerations such as containerization and scalability for modern architectures like microservices. By showcasing case studies and real-world examples of organizations transitioning from.NET Framework to.NET Core, it sheds light on motivations and challenges involved in shifts along, with the outcomes. Based upon these insights valuable recommendations are provided for developers and organizations; assisting them in making informed decisions regarding future C# application development projects. This study offers perspectives on the ever-changing environment of the.NET world and presents a roadmap for exploring the strategic considerations involved in opting for.NET Core instead of.NET Framework, in modern software development methodologies. Key Words: .NET, C#, .NET Core, .NET Framework, Case Studies, Differences. Download PDF

Title: COMPARATIVE ANALYSIS OF .NET CORE VS. .NET FRAMEWORK FOR DEVELOPING C# APPLICATIONS: DIFFERENCES AND ADVANTAGES
Author: Poe Ei Phyu, Thet Thet Aung, Khaing Thazin Nwe, Sharo Paw, Hlaing Htake Khaung Tin*
Keyword: .NET, C#, .NET Core, .NET Framework, Case Studies, Differences.
Page No: 01-09

Abstract: In the changing landscape of the.NET ecosystem software developers often face the decision of choosing between.NET Core and.NET Framework for developing C# applications. This study delves into the nua nces and benefits of opting for .NET Core over the Framework. It kicks things o? with a comparison that scrutinizes the architectural disparities, performance benchmarks, platform support, and dependency management features across both frameworks. The analysis focuses closely the support from the ecosystem and community to measure the presence of libraries and frameworks well as community involvement for both.NET. .Net Frameworks. It also delves into considerations such as containerization and scalability for modern architectures like microservices. By showcasing case studies and real-world examples of organizations transitioning from.NET Framework to.NET Core, it sheds light on motivations and challenges involved in shifts along, with the outcomes. Based upon these insights valuable recommendations are provided for developers and organizations; assisting them in making informed decisions regarding future C# application development projects. This study offers perspectives on the ever-changing environment of the.NET world and presents a roadmap for exploring the strategic considerations involved in opting for.NET Core instead of.NET Framework, in modern software development methodologies. Key Words: .NET, C#, .NET Core, .NET Framework, Case Studies, Differences. Download PDF

Title: A STUDY ON OPPORTUNITIES CREATED BY BIGDATA FOR INDUSTRIES
Author: Kumbhar Gajanan Shankar and Virendra Kumar Sharma
Keyword: Bigdata, Industries, opportunities, smart decision, improved customer service
Page No: 10-13

Abstract: In today’s world data has become important everywhere in industries. With the help of bigdata, industries are making smart decision, getting new micro markets, smart marketing analytics for long & sho rt term growth. Bigdata is now reached in every part of modern life & into business area. Companies in any industry can use bigdata to enhance their effectiveness, their marketing & products which lead the career opportunities in this field are limitless [5]. The capabilities of bigdata platform creating opportunities for industries like medicine, retail, construction, banking and transportation. By coupling with bigdata major advantages are achieved by businesses now days. Its improving the operational efficiency of businesses with much more improved customer services which is heart of any business for new products of any business with new customers and new markets. Key Words: Bigdata, Industries, opportunities, smart decision, improved customer service Download PDF

Title: A STUDY ON OPPORTUNITIES CREATED BY BIGDATA FOR INDUSTRIES
Author: Kumbhar Gajanan Shankar and Virendra Kumar Sharma
Keyword: Bigdata, Industries, opportunities, smart decision, improved customer service
Page No: 10-13

Abstract: In today’s world data has become important everywhere in industries. With the help of bigdata, industries are making smart decision, getting new micro markets, smart marketing analytics for long & sho rt term growth. Bigdata is now reached in every part of modern life & into business area. Companies in any industry can use bigdata to enhance their effectiveness, their marketing & products which lead the career opportunities in this field are limitless [5]. The capabilities of bigdata platform creating opportunities for industries like medicine, retail, construction, banking and transportation. By coupling with bigdata major advantages are achieved by businesses now days. Its improving the operational efficiency of businesses with much more improved customer services which is heart of any business for new products of any business with new customers and new markets. Key Words: Bigdata, Industries, opportunities, smart decision, improved customer service Download PDF

Title: A DEMOGRAPHIC STUDY TO DEVELOP A PREDICTION TOOL FOR LIVER DISEASE DUE TO ALCOHOL CONSUMPTION AMONGST DIFFERENT AGE GROUPS IN FIVE ETHNIC GROUPS OF ASSAM
Author: Kaushik Parashar Sharma, Dola Das, Debraj Chowdhury, Bandana Sarma, Susmita Dey*
Keyword: Liver disease, Alcohol consumption, Age-wise, Ethnic, Percentage.
Page No: 14-19

Abstract: Considering the significance of prevalence of liver disease, the present investigation was undertaken to develop a prediction tool of liver disease in five different ethnic groups of Assam, India. The occurrence of cirrhosis among these people is also not uncommon. It is therefore necessary to draw a relation between alcohol consumption and their liver condition this study was conducted taking into account some major indigenous ethnic groups of Assam, which are Assamese, Bengali, Bodo, Tea Tribe and Nepali. Subsequently, the survey was focused on highlighting ‘alcohol consumption’ as one of the primary causes of liver diseases, including liver cirrhosis in various ethnic groups, across Assam. Samples were collected from alcoholic individuals suffering from liver diseases, belonging from five different ethnic groups of Assam. The data was further subjected to statistical analysis and ANOVA: Single factor test was performed to check the significance of the study. Key Words: Liver disease, Alcohol consumption, Age-wise, Ethnic, Percentage. Download PDF

Title: A DEMOGRAPHIC STUDY TO DEVELOP A PREDICTION TOOL FOR LIVER DISEASE DUE TO ALCOHOL CONSUMPTION AMONGST DIFFERENT AGE GROUPS IN FIVE ETHNIC GROUPS OF ASSAM
Author: Kaushik Parashar Sharma, Dola Das, Debraj Chowdhury, Bandana Sarma, Susmita Dey*
Keyword: Liver disease, Alcohol consumption, Age-wise, Ethnic, Percentage.
Page No: 14-19

Abstract: Considering the significance of prevalence of liver disease, the present investigation was undertaken to develop a prediction tool of liver disease in five different ethnic groups of Assam, India. The occurrence of cirrhosis among these people is also not uncommon. It is therefore necessary to draw a relation between alcohol consumption and their liver condition this study was conducted taking into account some major indigenous ethnic groups of Assam, which are Assamese, Bengali, Bodo, Tea Tribe and Nepali. Subsequently, the survey was focused on highlighting ‘alcohol consumption’ as one of the primary causes of liver diseases, including liver cirrhosis in various ethnic groups, across Assam. Samples were collected from alcoholic individuals suffering from liver diseases, belonging from five different ethnic groups of Assam. The data was further subjected to statistical analysis and ANOVA: Single factor test was performed to check the significance of the study. Key Words: Liver disease, Alcohol consumption, Age-wise, Ethnic, Percentage. Download PDF

Title: SYNTHESIS CHARACTERIZATION AND PHARMACOLOGICAL EVALUATION OF SOME PYRAZOLIDINEDIONE SUBSTITUTED THIOCROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS
Author: Surbhi Tiwari, Reetesh Yadav, Deepak Patel
Keyword: Pyrazolidinedione Ring, Anti-Inflammatory, Synthesis, TLC, NMR
Page No: 20-28

Abstract: All the newly synthesized compounds were characterized by their physical properties and spectral data. The purity of newly synthesized compounds was confirmed by TLC. Spectral analysis (IR, 1H, 13C NM R and Mass spectrometry) of the compounds adequately supported the structures of the synthesized compounds. The appearance of a band between 1764-1623 cm-1 (C=O) in the IR spectra; a singlet peak at d value 4.3-5.0 for two protons of CH2 of the pyrazolidinedione ring in the 1H NMR spectra and a peak at d 41.7-46.9 for carbon of CH2 of the pyrazolidinedione ring supports the formation of pyrazolidinedione substituted thiochromene derivatives (20-35). Molecular ion peaks of the synthesized pyrazolidinedione substituted thiochromene derivatives were obtained on the mass spectra, corresponds with their structures. These spectral data satisfactorily supports the formation of the title compounds. The formation of thiochromene and pyrazolidinedione moieties is supported by the reaction mechanism.Download PDF

Title: SYNTHESIS CHARACTERIZATION AND PHARMACOLOGICAL EVALUATION OF SOME PYRAZOLIDINEDIONE SUBSTITUTED THIOCROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS
Author: Surbhi Tiwari, Reetesh Yadav, Deepak Patel
Keyword: Pyrazolidinedione Ring, Anti-Inflammatory, Synthesis, TLC, NMR
Page No: 20-28

Abstract: All the newly synthesized compounds were characterized by their physical properties and spectral data. The purity of newly synthesized compounds was confirmed by TLC. Spectral analysis (IR, 1H, 13C NM R and Mass spectrometry) of the compounds adequately supported the structures of the synthesized compounds. The appearance of a band between 1764-1623 cm-1 (C=O) in the IR spectra; a singlet peak at d value 4.3-5.0 for two protons of CH2 of the pyrazolidinedione ring in the 1H NMR spectra and a peak at d 41.7-46.9 for carbon of CH2 of the pyrazolidinedione ring supports the formation of pyrazolidinedione substituted thiochromene derivatives (20-35). Molecular ion peaks of the synthesized pyrazolidinedione substituted thiochromene derivatives were obtained on the mass spectra, corresponds with their structures. These spectral data satisfactorily supports the formation of the title compounds. The formation of thiochromene and pyrazolidinedione moieties is supported by the reaction mechanism.Download PDF

Title: SPECTROPHOTOMETRIC SIMULTANEOUS QUANTITATIVE ANALYTICAL ANALYSIS METHOD FOR PCM-MET DEVELOPED AND VALIDATED
Author: Rahul Molla, Arindam Sarkar and Sanchita Mandal*
Keyword: Paracetamol, Metronidazole, Simultaneous equation method, Q-Analysis, ICH guidelines
Page No: 29-39

Abstract: Combination of two API Paracetamol (PCM) and Metronidazole (MET) were analysed by simple, particular, accurate and reproducible spectrophotometric method developed and validated following the ICH q2(R 1) guideline. MET is a broad-spectrum antibiotic, antiprotozoal and PCM is an analgesic, antipyretic. In method 1 Simultaneous equation method ?-max of PCM and MET were found 243 nm and 320nm respectively. While method 2 in MET and PCM involves formation of “Isoabsorptive point” at 264nm (Q-analysis) and ?-max of MET 320nm were selected. Linearity of both MET and PCM were selected in 2 to10 microgram/ml range. The Beer lambert’s law limit for each drug individually, in mixture and marketed formulation was within this concentration series same as linearity range. Current methods were developed and validated depending on the parameters Range and Linearity, Precision (repeatability, interday, intraday, reproducibility), Accuracy, LOD, LOQ, Ruggedness, Robustness, recovery parameters. Range and linearity 2-10, intraday precision for PCM & MET was 1.613 and 0.700 respectively, interday precision of PCM & MET was 4.03 and 3.05 respectively, accuracy (50%, 100%, 150% level of increase, it was found for paracetamol 97.04%, 99.4%, 99.03% and for metronidazole 99.16%, 107%, 99.1% respectively, LOD for PCM & MET was 0.546 and 0.240 respectively, LOQ for PCM & MET was 1.65 and 0.729 respectively. It was found Q absorbance method shows % recovery 96-105% and Simultaneous equation 96-101% in terms of biasness as the deviation is less in Q-absorbance method, more in simultaneous method. So, it was suggested Q absorbance techniques will give more accuracy for routine analysis of both API in combination. Key words: Paracetamol, Metronidazole, Simultaneous equation method, Q-Analysis, ICH guidelines. Download PDF

Title: SPECTROPHOTOMETRIC SIMULTANEOUS QUANTITATIVE ANALYTICAL ANALYSIS METHOD FOR PCM-MET DEVELOPED AND VALIDATED
Author: Rahul Molla, Arindam Sarkar and Sanchita Mandal*
Keyword: Paracetamol, Metronidazole, Simultaneous equation method, Q-Analysis, ICH guidelines
Page No: 29-39

Abstract: Combination of two API Paracetamol (PCM) and Metronidazole (MET) were analysed by simple, particular, accurate and reproducible spectrophotometric method developed and validated following the ICH q2(R 1) guideline. MET is a broad-spectrum antibiotic, antiprotozoal and PCM is an analgesic, antipyretic. In method 1 Simultaneous equation method ?-max of PCM and MET were found 243 nm and 320nm respectively. While method 2 in MET and PCM involves formation of “Isoabsorptive point” at 264nm (Q-analysis) and ?-max of MET 320nm were selected. Linearity of both MET and PCM were selected in 2 to10 microgram/ml range. The Beer lambert’s law limit for each drug individually, in mixture and marketed formulation was within this concentration series same as linearity range. Current methods were developed and validated depending on the parameters Range and Linearity, Precision (repeatability, interday, intraday, reproducibility), Accuracy, LOD, LOQ, Ruggedness, Robustness, recovery parameters. Range and linearity 2-10, intraday precision for PCM & MET was 1.613 and 0.700 respectively, interday precision of PCM & MET was 4.03 and 3.05 respectively, accuracy (50%, 100%, 150% level of increase, it was found for paracetamol 97.04%, 99.4%, 99.03% and for metronidazole 99.16%, 107%, 99.1% respectively, LOD for PCM & MET was 0.546 and 0.240 respectively, LOQ for PCM & MET was 1.65 and 0.729 respectively. It was found Q absorbance method shows % recovery 96-105% and Simultaneous equation 96-101% in terms of biasness as the deviation is less in Q-absorbance method, more in simultaneous method. So, it was suggested Q absorbance techniques will give more accuracy for routine analysis of both API in combination. Key words: Paracetamol, Metronidazole, Simultaneous equation method, Q-Analysis, ICH guidelines. Download PDF

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	Fast reviewing process: Adopting the fast reviewing process we communicate with authors at all stages till publication. Proactive teams of reviewers from National and International front help us to complete the process within the time.
	IJSR dose not impose any publication fee or processing charges.